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History and Information

Alpha Hydroxy Profile


Alpha hydroxy acids are natural acids found in foods such as citric acid (citrus fruits), glycolic acid (sugarcane), lactic acid (sour milk), malic acid (apples), tartaric acid (grapes), gluconolactone and others. Hyperkeratinization (increased bonding of dead skin cells together) is thought to contribute to acne, dry skin, and photo-aging. Alpha hydroxy acids work by exfoliating the top layers of dead skin cells, and seem to improve the appearance of aging skin by increasing smoothness and reducing dark spots.

Practical Uses
Topically, alpha hydroxy acids are used for moisturizing and removing dead skin cells, for treating acne and improving the appearance of atrophic acne scars, improving the appearance of photo-aged skin, and firming and smoothing skin. Alpha hydroxy acids are also used to treat xerosis (pathologic dry skin), ichthyosis (disorder with hyperkeratinization and scaling of skin), and decreasing hyperpigmentation associated with melasma.


Cautions
Topically, alpha hydroxy acids are generally well tolerated when used in concentrations at or below 10%). However, these products can increase sensitivity to the sun and ultraviolet (UV) light, which can increase damage to the skin, and after long-term use, might increase the risk of skin cancer. It is important to protect yourself from the sun by using sunscreen and/or protective clothing. It is recommended to patch test the product on a small area of skin before applying it to a larger area. Adverse reactions can range from mild irritation, a tingling sensation, and stinging to severe redness, swelling, itching, blistering, bleeding, rash, burns, and skin discoloration. Higher concentrations can cause severe skin irritation, burning, sloughing, and limited frosting and whitening to scar areas which sometimes results in transient hyperpigmentation.
Summarized
From
Natural Medicines Comprehensive Database: Alpha Hydroxy Monograph accessed at http://naturaldatabase.therapeuticresearch.com on January 16, 2011.
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